Background: The breast is an uncommon site for metastatic disease because, due to its anatomical composition, it contains large areas of fibrous tissue with relatively little blood supply and the route of dissemination of most metastases is usually hematogenous. They represent 0.5-6% of all breast tumors, most commonly presenting in women between 20-85 years old with an average of 60 years old. Most of it has its origin in lymphoma (17%), melanoma (15%), rhabdomyosarcoma (12%), lung carcinoma (8%), ovarian tumors (8%), renal cell tumors (5%), leukemia (4%), thyroid and cervical tumors (4%), intestinal carcinoid tumor (3%), squamous cell carcinoma of the head and neck (3%) and leiomyosarcomas (2%).
Learning Objectives: 1- Know the oncological entities that most frequently cause metastasis to the breast. 2. Characterize the behavior of metastatic lesions in the breast in a multimodal imaging study (mammography, ultrasound, magnetic resonance imaging, PET-CT). 3- Recognize the characteristics by immunohistochemistry of metastatic tumors of the breast
Abstract Content/Results: A series of 24 cases of breast metastasis is presented, covering all reported types, performing a correlation of the clinical, multimodal imaging and histopathological manifestations of the lesions, describing the most common form of metastasis of the primary neoplasia and how this influences the form of presentation thereof.
Conclusion: In imaging studies, it is usually similar to primary breast cancer, its diagnosis being a challenge, as it can manifest as hypoechoic nodules, with a circumscribed margin, round or oval shape, solitary or multiple, without calcifications or architectural distortion, located superficially in the breast. and without association with changes in the skin or nipple. They are a late manifestation of the disease, so they generally have a poor prognosis and survival of one year from diagnosis. Multidisciplinary work is essential in its diagnostic approach since knowing the patient's oncological history will help guide the imaging and pathological examination.